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ABOUT YolTech

ABOUT YolTech

YolTech Therapeutics is a clinical-stage in vivo gene editing company committed to pioneering the next generation of precision genetic medicines. YolTech’s differentiated platform combines innovative gene editing technologies with a proprietary advanced lipid nanoparticle (LNP) delivery system to address a broad range of serious genetic, metabolic and autoimmune diseases.

 
A core pillar of YolTech’s mission is the development of robust internal capabilities, including end-to-end manufacturing, to ensure the highest standards of quality and scalability.

 
YolTech’s growing pipeline includes multiple clinical-stage programs, including YOLT-201, which is being developed for the treatment Transthyretin Amyloidosis (ATTR), YOLT-202 for Alpha-1 Antitrypsin Deficiency (AATD), YOLT-203 for Primary Hyperoxaluria (PH1), YOLT-204 for Beta Thalassemia/Sickle Cell Disease and YOLT-101 for Familial Hypercholesterolemia (FH). As a company dedicated to transforming the treatment landscape, YolTech continues to push the boundaries of what is possible in gene editing.

DEVELOPMENT MILESTONES

  • 2026
    • Feb

      FDA RMAT Designation for YOLT-203

    • Mar

      FDA IND Clearance for YOLT-202

    • May

      FDA RMAT Designation for YOLT-202

  • 2025
    • Apr

      FDA ODD designation for YOLT-202

    • Jun

      FDA IND clearance for YOLT-101

    • Jul

      NMPA IND Clearance for YOLT-101

    • Jul

      EMA ODD designation for YOLT-203

    • Nov

      FDA IND clearance for YOLT-203 Pivotal

  • 2024
    • Feb

      Patent granted for base editor

    • Mar

      NMPA IND Clearance for YOLT-201

    • Apr

      Patent granted for CRISPR/Cas

    • Apr

      First Patient Dosed for YOLT-101

    • Aug

      First Patient Dosed for YOLT-203

    • Sep

      FDA RPDD and ODD designation for YOLT-203

  • 2023
    • Mar

      GMP manufacturing facility established in Nanjing

    • Dec

      First patiend dosed for YOLT-201

  • 2021
    • Jul

      YolTech founded in Shanghai

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    2026
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    2025
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    2024
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    2023
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    2021