• Excellence

  • Tenacious

  • Relentless

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PIPELINE

Metabolic Disease

Program
Indication
Target Gene
Delivery
Discovery
Lead Optimization
IND Enabling
Clinical Stage
Partners

Genetic Disease

Program
Indication
Target Gene
Delivery
Discovery
Lead Optimization
IND Enabling
Clinical Stage
Partners

Infectious Disease

Program
Indication
Target Gene
Delivery
Discovery
Lead Optimization
IND Enabling
Clinical Stage
Partners

Metabolic Disease

Program

YOLT-101

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  • Indication

    Familial Hypercholesterolemia (FH)

  • Target Gene

    PCSK9

  • Delivery

    In vivo   LNP

  • Partners

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Discovery
Lead Optimization
IND Enabling
Clinical Stage
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Program

YOLT-102

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  • Indication

    ASCVD

  • Target Gene

    Undisclosed

  • Delivery

    In vivo  LNP

  • Partners

    d1_logo.png
Discovery
Lead Optimization
IND Enabling
Clinical Stage
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Program

YOLT-103

  • Indication

    Undisclosed

  • Target Gene

    Undisclosed

  • Delivery

    In vivo  LNP

  • Partners

    d1_logo.png
Discovery
Lead Optimization
IND Enabling
Clinical Stage
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Genetic Disease

Program

YOLT-201
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  • Indication

    Transthyretin Amyloidosis (ATTR)

  • Target Gene

    TTR

  • Delivery

    In vivo  LNP

  • Partners

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Discovery
Lead Optimization
IND Enabling
Clinical Stage
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Program

YOLT-202
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  • Indication

    Alpha-1 Antitrypsin Deficiency (AATD)

  • Target Gene

    AAT

  • Delivery

    In vivo  LNP

  • Partners

    d1_logo.png
Discovery
Lead Optimization
IND Enabling
Clinical Stage
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Program

YOLT-203
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  • Indication

    Primary Hyperoxaluria (PH1)

  • Target Gene

    HAO1

  • Delivery

    In vivo  LNP

  • Partners

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Discovery
Lead Optimization
IND Enabling
Clinical Stage
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Program

YOLT-204
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  • Indication

    Undisclosed

  • Target Gene

    Undisclosed

  • Delivery

    In vivo  LNP

  • Partners

    d1_logo.png
Discovery
Lead Optimization
IND Enabling
Clinical Stage
d1_icon004.svg

Program

YOLT-205
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  • Indication

    HAE

  • Target Gene

    PAH

  • Delivery

    In vivo  LNP

  • Partners

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Discovery
Lead Optimization
IND Enabling
Clinical Stage
d1_icon004.svg

Infectious Disease

Program

YOLT-301
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  • Indication

    Hepatitis B

  • Target Gene

    Undisclosed

  • Delivery

    In vivo  LNP

  • Partners

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Discovery
Lead Optimization
IND Enabling
Clinical Stage
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Program

YOLT-302
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  • Indication

    Undisclosed

  • Target Gene

    Undisclosed

  • Delivery

    In vivo  LNP

  • Partners

    d1_logo.png
Discovery
Lead Optimization
IND Enabling
Clinical Stage
d1_icon01.svg