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Science Advances
Spleen-targeted NeoPol-mL242 mRNA vaccine induces robust T-cell responses in a hepatocellular carcinoma model
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Journal of Nanobiotechnology
In vivo genome editing of human haematopoietic stem cells for treatment of blood disorders using mRNA delivery
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Nature Biomedical Engineering
Sequential Amino Acid Mutagenesis-Driven De Novo Evolution of Adenine Deaminases Enables Efficient In Vivo Base Editing in Primate
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bioRxiv
Base Editing Gene Therapy for Heterozygous Familial Hypercholesterolemia
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MedRxiv
Efficient and safe in vivo treatment of primary hyperoxaluria type 1 via LNP-CRISPR-Cas9-mediated glycolate oxidase disruption
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Molecular Therapy
In vivo genome editing of human hematopoietic stem cells for treatment of blood disorders by mRNA delivery
2024
bioRxiv
Library-Assisted Evolution in Eukaryotic Cells Yield Adenine Base Editors with Enhanced Editing Specificity
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Advanced Science
